Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAF1 | P21675 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20942542 | 1.00 | TAF1 (0.65) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL20942536 | 0.96 | TAF1 (0.60) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL20942538 | 0.93 | NPC1 (0.60) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL20942203 | 0.86 | TAF1 (0.49) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL20942502 | 0.82 | USP2 (0.67) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19276574 | 0.82 | BRD4 (0.52) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20942233 | 0.81 | ALDH1A1 (0.59) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL19276576 | 0.81 | NPC1 (0.60) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL20942497 | 0.81 | NPC1 (0.58) | TAF1RAB9ANPC1MAPTTP53 | |
| SCHEMBL20942221 | 0.79 | TAF1 (1.00) | TAF1RAB9ANPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4430192-A2 | LNCRNA TRANSCRIPTS IN MELANOMAGENESIS | The Regents of the University of California (US) | 2024-09-18 | — | — | EP | claimed |
| WO-2023086552-A2 | LNCRNA TRANSCRIPTS IN MELANOMAGENESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-19 | — | — | WO | claimed |
| US-20250197864-A1 | LNCRNA TRANSCRIPTS IN MELANOMAGENESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-06-19 | — | — | US | disclosed |
| US-20250011881-A1 | MYC-HSF1 DUAL AMPLIFICATION AS A BIOMARKER FOR CANCER TREATMENT | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-01-09 | — | — | US | disclosed |
| US-20240309458-A1 | MYC-HSF1 DUAL AMPLIFICATION AS A BIOMARKER FOR CANCER TREATMENT | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-09-19 | — | — | US | disclosed |
| EP-4430192-A2 | LNCRNA TRANSCRIPTS IN MELANOMAGENESIS | The Regents of the University of California (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086552-A2 | LNCRNA TRANSCRIPTS IN MELANOMAGENESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-19 | — | — | WO | disclosed |