Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19277665 | 1.00 | UGT2B7 (0.37) | UGT2B7IDO1CYP3A4CYP2D6CYP2B6 | |
| SCHEMBL15769664 | 0.81 | — | — | |
| SCHEMBL19276938 | 0.80 | UGT2B7 (0.36) | UGT2B7 | |
| SCHEMBL9998579 | 0.77 | UGT2B7 (0.35) | UGT2B7IDO1 | |
| SCHEMBL15184686 | 0.75 | TP53 (0.52) | UGT2B7IDO1TDO2 | |
| SCHEMBL10596591 | 0.75 | TP53 (0.52) | UGT2B7IDO1TDO2 | |
| SCHEMBL420093 | 0.75 | TP53 (0.52) | UGT2B7IDO1TDO2 | |
| SCHEMBL13839652 | 0.75 | TP53 (0.52) | UGT2B7IDO1TDO2 | |
| SCHEMBL12889705 | 0.72 | UGT2B7 (0.36) | UGT2B7 | |
| SCHEMBL19276892 | 0.72 | UGT2B7 (0.33) | UGT2B7IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898309-A | Tricyclic compounds as immunomodulators | 正大天晴药业集团股份有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-108884103-B | Tricyclic compounds as immunomodulators | 正大天晴药业集团股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| WO-2017140274-A1 | TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR | 正大天晴药业集团股份有限公司 | 2017-08-24 | — | — | WO | disclosed |