Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.55 |
| ▸ | FSHR | P23945 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14633951 | 0.88 | DRD2 (0.61) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL19291178 | 0.87 | DRD2 (0.59) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14634038 | 0.87 | DRD2 (0.59) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14634003 | 0.87 | DRD2 (0.59) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14634064 | 0.86 | DRD2 (0.56) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14633906 | 0.86 | DRD2 (0.61) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14634014 | 0.85 | DRD2 (0.56) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14633918 | 0.85 | DRD2 (0.56) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14633515 | 0.84 | DRD2 (0.56) | DRD2DRD3ADRA1AFSHRNPC1 | |
| SCHEMBL14633895 | 0.83 | DRD2 (0.54) | DRD2DRD3ADRA1AFSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263568-A1 | BENZAMIDES | Merck Patent GmbH (DE) | 2018-01-03 | — | — | EP | disclosed |
| EP-2734517-B1 | BENZAMIDES | MERCK PATENT GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |