Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Oxocallitrisic Acid, Methyl Ester SCHEMBL15339316 | 0.85 | CYP3A4 (1.00) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL2728587 | 0.85 | CYP3A4 (0.70) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL2728589 | 0.85 | CYP3A4 (0.70) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL19283122 | 0.82 | KARS1 (0.68) | CYP3A4MAPTALOX15KARS1CCNE1 | |
| SCHEMBL20364223 | 0.82 | CYP3A4 (0.78) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL3212768 | 0.82 | CYP3A4 (0.78) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL15344775 | 0.82 | CYP3A4 (0.81) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL19293731 | 0.80 | CYP3A4 (0.66) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL14201538 | 0.79 | CYP3A4 (0.74) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL14207873 | 0.79 | CYP3A4 (0.74) | CYP3A4ALDH1A1MAPTALOX15AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247409-A1 | ABIETANE-TYPE DITERPENOIDS | UNIVERSITY OF HELSINKI (FI) | 2017-08-31 | — | — | US | disclosed |
| US-20170247409-A1 | ABIETANE-TYPE DITERPENOIDS | UNIVERSITY OF HELSINKI (FI) | 2017-08-31 | — | — | US | disclosed |
| US-20170247409-A1 | ABIETANE-TYPE DITERPENOIDS | UNIVERSITY OF HELSINKI (FI) | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247409-A1 | ABIETANE-TYPE DITERPENOIDS | CROCC, ROS1, RDX | CYP3A4 1531/4885ALDH1A1 814/4885MAPT 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.