SCHEMBL19283201

SCHEMBL19283201

CCN(c1ccccc1)c1c(C)cc(C)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 4/20 0.48
TP53 P04637 2/20 0.41
MAPT P10636 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NR3C2 P08235 1/20 0.41
TSHR P16473 3/20 0.41
HCN1 O60741 2/20 0.41
HCN4 Q9Y3Q4 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
APAF1 O14727 1/20 0.41
CASP3 P42574 1/20 0.41
CASP6 P55212 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608990 0.82 NR3C2 (0.46) CRHR1TP53MAPTCRHBPCRHR2
SCHEMBL2360359 0.80 CRHR1 (0.46) CRHR1MAPTALDH1A1
SCHEMBL20404315 0.80 KCNH2 (0.49)
SCHEMBL22338052 0.79 TP53 (0.44) CRHR1TP53MAPTCRHBPCRHR2
SCHEMBL25514040 0.79 NPC1 (0.43) CRHR1TP53L3MBTL1ALDH1A1DHFR
SCHEMBL3477723 0.79 CYP1A2 (0.41) CRHR1MAPTNPSR1TSHRCYP1A2
SCHEMBL22550359 0.79 CYP1A2 (0.41) CRHR1MAPTNPSR1TSHRCYP1A2
SCHEMBL21970152 0.78 KDM4E (0.44) CRHR1MAPTTSHRL3MBTL1ALDH1A1
SCHEMBL409370 0.78 NR3C2 (0.57) TP53MAPTCRHBPCRHR2NPSR1
SCHEMBL6567347 0.78 NR3C2 (0.57) TP53MAPTCRHBPCRHR2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351576-B1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2020-05-06 EP disclosed
US-10358567-B2 Compound, ink, ink cartridge and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2019-07-23 US disclosed
EP-3351576-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company Limited (JP) 2018-07-25 EP disclosed
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2017-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10358567-B2 Compound, ink, ink cartridge and ink jet recording method JAK1, JAK2, ETV6 CRHR1 1989/4885TP53 1986/4885MAPT 3245/4885
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD JAK1, JAK2, ETV6 CRHR1 1989/4885TP53 1986/4885MAPT 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.