Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286187 | 0.90 | MEN1 (0.42) | ALDH1A1MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL19286178 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL19286293 | 0.78 | — | — | |
| SCHEMBL19286285 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL19286179 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL19286273 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL17470029 | 0.72 | MEN1 (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL19286180 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL19286191 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL19286176 | 0.71 | MAPT (0.50) | ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |