Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286275 | 0.94 | MAPT (0.43) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19286246 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19286188 | 0.80 | MAPT (0.42) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL17470124 | 0.80 | LMNA (0.39) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19286313 | 0.79 | SMN1; SMN2 (0.43) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19286297 | 0.78 | HTT (0.41) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL17470026 | 0.76 | MAPT (0.40) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL17470023 | 0.75 | MAPT (0.40) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL17448378 | 0.74 | LMNA (0.58) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL7520490 | 0.74 | LMNA (0.58) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |