Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MAX | P61244 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286244 | 0.82 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286176 | 0.80 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL17470039 | 0.80 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL1754979 | 0.78 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286246 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286188 | 0.72 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286275 | 0.71 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL17470114 | 0.71 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL1754959 | 0.71 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL23129658 | 0.71 | LMNA (0.46) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |