Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAX | P61244 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | UBE2M | P61081 | 2/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17470039 | 0.82 | MAPT (0.50) | LMNAALDH1A1HTTPAX8MAPT | |
| SCHEMBL19286176 | 0.82 | MAPT (0.50) | LMNAALDH1A1HTTPAX8MAPT | |
| SCHEMBL19286237 | 0.77 | LMNA (0.42) | LMNAALDH1A1HTTPAX8MAPT | |
| SCHEMBL19286188 | 0.77 | MAPT (0.42) | LMNAALDH1A1HTTPAX8MAPT | |
| SCHEMBL19286228 | 0.71 | MAPKAPK2 (0.37) | TACR1 | |
| SCHEMBL15012994 | 0.71 | KDM4E (0.33) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16449929 | 0.71 | KDM4E (0.33) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19286312 | 0.71 | KDM4E (0.33) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16327184 | 0.70 | TACR1 (0.38) | TACR1KCNH2 | |
| SCHEMBL17470038 | 0.69 | MAPT (0.41) | LMNAALDH1A1HTTPAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |