Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286287 | 0.84 | CYP3A4 (0.47) | RECQLCYP2C19CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL19286262 | 0.81 | CYP2C19 (0.36) | RECQLGAAHPGDCYP2C19CYP3A4 | |
| SCHEMBL17470035 | 0.74 | GAA (0.33) | RECQLGAA | |
| SCHEMBL16317652 | 0.74 | GAA (0.33) | RECQLGAA | |
| SCHEMBL19286290 | 0.72 | GAA (0.50) | GAACYP3A4TSHRLMNA | |
| SCHEMBL17470180 | 0.72 | CYP2C19 (0.31) | RECQLGAAHPGDCYP2C19CYP3A4 | |
| SCHEMBL25159618 | 0.71 | KDM1A (0.36) | RECQLCYP3A4TSHR | |
| SCHEMBL19286285 | 0.71 | ALDH1A1 (0.34) | RECQLLMNA | |
| SCHEMBL17470033 | 0.71 | HIF1A (0.37) | RECQLGAACYP2D6CYP1A2LMNA | |
| SCHEMBL19286298 | 0.71 | HIF1A (0.37) | RECQLGAACYP2D6CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |