Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410129 | 0.85 | CASR (0.59) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL8285877 | 0.85 | CASR (0.59) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL10305652 | 0.85 | CASR (0.59) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL413322 | 0.85 | CASR (0.59) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL7862921 | 0.85 | CASR (0.59) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL13740795 | 0.83 | CASR (0.58) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL7903255 | 0.83 | CASR (0.58) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL14438388 | 0.83 | CASR (0.58) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL18475311 | 0.83 | CASR (0.43) | CASRPOLBSMN1; SMN2HTR1AADRA2B | |
| SCHEMBL12870263 | 0.83 | CASR (0.58) | CASRPOLBSMN1; SMN2HTR1AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |