Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 6/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508849 | 1.00 | CASR (0.58) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL8285877 | 0.83 | CASR (0.59) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL410129 | 0.83 | CASR (0.59) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL413322 | 0.83 | CASR (0.59) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL10305652 | 0.83 | CASR (0.59) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL7862921 | 0.83 | CASR (0.59) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL19286306 | 0.83 | CASR (0.59) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL13740795 | 0.81 | CASR (0.58) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL12870263 | 0.81 | CASR (0.58) | CASRAOC3POLBSMN1; SMN2MEN1 | |
| SCHEMBL14438388 | 0.81 | CASR (0.58) | CASRAOC3POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |