Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356497 | 0.92 | TACR3 (0.44) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL10349304 | 0.86 | POLB (0.47) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL14533617 | 0.84 | POLB (0.46) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL11357814 | 0.82 | POLB (0.49) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL8861456 | 0.82 | AOC3 (0.51) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL8100060 | 0.81 | CACNA2D1 (0.44) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL6024638 | 0.81 | POLB (0.47) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL20363507 | 0.80 | PPARG (0.41) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL2748316 | 0.79 | POLB (0.46) | POLBALDH1A1KDM4ETACR3SLC2A1 | |
| SCHEMBL10609195 | 0.79 | HRH1 (0.47) | POLBALDH1A1KDM4ETACR3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |