Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 2/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259100 | 0.93 | TACR3 (0.43) | POLBALDH1A1TACR3SLC2A1HTR2A | |
| SCHEMBL10349304 | 0.90 | POLB (0.47) | POLBALDH1A1KDM4ETACR3GPR88 | |
| SCHEMBL9272437 | 0.89 | AOC3 (0.44) | POLBALDH1A1TACR3MAPTHTR2A | |
| SCHEMBL13302608 | 0.82 | LMNA (0.46) | ALDH1A1KDM4EAOC3 | |
| SCHEMBL12312555 | 0.82 | LMNA (0.46) | ALDH1A1KDM4EAOC3 | |
| SCHEMBL172612 | 0.82 | LMNA (0.46) | ALDH1A1KDM4EAOC3 | |
| SCHEMBL11031006 | 0.82 | POLB (0.52) | POLBALDH1A1KDM4ETACR3GPR88 | |
| SCHEMBL14533617 | 0.81 | POLB (0.46) | POLBALDH1A1KDM4ETACR3GPR88 | |
| SCHEMBL19286307 | 0.81 | POLB (0.46) | POLBALDH1A1KDM4ETACR3GPR88 | |
| SCHEMBL11357814 | 0.79 | POLB (0.49) | POLBALDH1A1KDM4ETACR3GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957080-B1 | NOVEL ETHYLAMINE DERIVATIVES | FUJIMOTO BROTHERS CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |