Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.97 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614295 | 0.88 | MAPK1 (1.00) | MAPTL3MBTL1MAPK1ALDH1A1DCTPP1 | |
| SCHEMBL22778043 | 0.87 | MAPT (0.79) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL3616361 | 0.87 | MAPT (1.00) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL3616157 | 0.84 | MAPK1 (0.74) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL3616153 | 0.84 | MAPK1 (0.74) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL14825216 | 0.83 | MAPT (1.00) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL27967669 | 0.82 | MAPT (0.74) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL28300995 | 0.82 | MAPT (0.74) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL25855470 | 0.81 | HPGD (0.73) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL16284337 | 0.80 | HPGD (0.68) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744171-B2 | Positive allosteric modulators for melanocortin receptors | VANDERBILT UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |