Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286540 | 0.87 | KMT2A (0.32) | KMT2A | |
| SCHEMBL24834195 | 0.74 | — | — | |
| SCHEMBL10200648 | 0.73 | GRIN2D (0.39) | — | |
| SCHEMBL5962483 | 0.73 | GRIN2D (0.39) | KMT2A | |
| SCHEMBL29333443 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL20115154 | 0.67 | ALDH1A1 (0.38) | KMT2A | |
| SCHEMBL22618154 | 0.67 | KMT2A (0.40) | KMT2A | |
| SCHEMBL22871684 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL19226582 | 0.67 | TSHR (0.37) | — | |
| SCHEMBL10329908 | 0.66 | GRIN2D (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745321-B2 | Fused pyrimidine compound, intermediate, preparation method therefor, and composition and application thereof | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2017-08-29 | — | — | US | disclosed |