SCHEMBL19286716

SCHEMBL19286716

CC(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)CBr)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.53
▸ FOLH1 Q04609 9/20 0.48
▸ C3AR1 Q16581 1/20 0.41
▸ ALB P02768 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14239852 1.00 GLP1R (0.53) GLP1RFOLH1C3AR1ALB
SCHEMBL15850016 0.91 GLP1R (0.59) GLP1RFOLH1C3AR1ALB
SCHEMBL14238762 0.91 GLP1R (0.56) GLP1RFOLH1C3AR1
SCHEMBL19286722 0.91 GLP1R (0.56) GLP1RFOLH1C3AR1
SCHEMBL15871519 0.91 GLP1R (0.56) GLP1RFOLH1C3AR1
SCHEMBL15850010 0.90 GLP1R (0.60) GLP1RFOLH1C3AR1
SCHEMBL19513194 0.90 GLP1R (0.55) GLP1RFOLH1C3AR1ALB
SCHEMBL19261665 0.90 GLP1R (0.57) GLP1RFOLH1C3AR1
SCHEMBL15849993 0.90 GLP1R (0.60) GLP1RFOLH1C3AR1
SCHEMBL15850000 0.90 GLP1R (0.60) GLP1RFOLH1C3AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9744213-B2 FGF21 derivatives and uses thereof NOVO NORDISK A/S (DK) 2017-08-29 — — US disclosed
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