Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.59 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155407 | 0.92 | GLP1R (0.62) | GLP1RALBFOLH1C3AR1 | |
| SCHEMBL19286716 | 0.91 | GLP1R (0.53) | GLP1RALBFOLH1C3AR1 | |
| SCHEMBL14239852 | 0.91 | GLP1R (0.53) | GLP1RALBFOLH1C3AR1 | |
| SCHEMBL15871502 | 0.91 | GLP1R (0.61) | GLP1RALBFOLH1C3AR1 | |
| SCHEMBL15850015 | 0.91 | GLP1R (0.66) | GLP1RFOLH1 | |
| SCHEMBL16478790 | 0.90 | GLP1R (0.57) | GLP1RALBFOLH1C3AR1 | |
| SCHEMBL19261649 | 0.89 | GLP1R (0.58) | GLP1RALBFOLH1C3AR1 | |
| SCHEMBL15871463 | 0.88 | GLP1R (0.68) | GLP1RFOLH1 | |
| SCHEMBL16478842 | 0.88 | GLP1R (0.65) | GLP1RFOLH1 | |
| SCHEMBL19286722 | 0.87 | GLP1R (0.56) | GLP1RFOLH1C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765130-B2 | Antagonistic DR3 ligands | NOVO NORDISK A/S (DK) | 2014-07-01 | — | — | US | disclosed |