Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763866 | 0.82 | TSHR (0.38) | TSHRALDH1A1TDP1 | |
| SCHEMBL4270411 | 0.82 | TSHR (0.43) | TSHRALDH1A1TDP1 | |
| SCHEMBL2219107 | 0.78 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL14338723 | 0.78 | — | — | |
| SCHEMBL19019638 | 0.77 | TSHR (0.43) | TSHR | |
| SCHEMBL11862718 | 0.76 | — | — | |
| SCHEMBL23045214 | 0.76 | TSHR (0.33) | TSHRALDH1A1TDP1 | |
| SCHEMBL14261872 | 0.76 | TSHR (0.56) | TSHRALDH1A1TDP1 | |
| SCHEMBL6855046 | 0.76 | TSHR (0.56) | TSHRALDH1A1TDP1 | |
| SCHEMBL13691435 | 0.76 | TRPA1 (0.42) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592073-B1 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND THEIR USE | AERPIO THERAPEUTICS INC (US) | 2017-08-30 | — | — | EP | disclosed |