⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980443 | 0.92 | — | — | |
| SCHEMBL28146195 | 0.92 | — | — | |
| SCHEMBL27988420 | 0.92 | — | — | |
| SCHEMBL14013414 | 0.74 | — | — | |
| SCHEMBL5005539 | 0.70 | — | — | |
| SCHEMBL30787778 | 0.69 | — | — | |
| SCHEMBL27993266 | 0.69 | — | — | |
| SCHEMBL386696 | 0.65 | — | — | |
| SCHEMBL3630149 | 0.65 | — | — | |
| SCHEMBL737404 | 0.65 | HRH4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787433-B2 | Pyridazine derivatives as EAAT2 activators | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190040040-A1 | PYRIDAZINE DERIVATIVES AS EAAT2 ACTIVATORS | OHIO STATE UNIVERSITY | 2019-02-07 | — | — | US | disclosed |
| EP-3402793-A1 | PYRIDAZINE DERIVATIVES AS EAAT2 ACTIVATORS | The Brigham and Women's Hospital, Inc. (US) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017123991-A1 | PYRIDAZINE DERIVATIVES AS EAAT2 ACTIVATORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-07-20 | — | — | WO | disclosed |
| US-8003699-B2 | Amide compound and use thereof for controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-23 | — | — | US | disclosed |
| US-7956010-B2 | Amide compound and use thereof for controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20100137445-A1 | PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD | SUMITOMO CHEMICAL COMPANY ,LIMITED | 2010-06-03 | — | — | US | disclosed |
| US-20100137376-A1 | AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100105647-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-04-29 | — | — | US | disclosed |
| EP-2179651-A1 | PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD | Sumitomo Chemical Company, Limited (JP) | 2010-04-28 | — | — | EP | disclosed |
| EP-2174931-A1 | AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-20100048701-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2154124-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | Sumitomo Chemical Company, Limited (JP) | 2010-02-17 | — | — | EP | disclosed |
| EP-2151432-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | Sumitomo Chemical Company, Limited (JP) | 2010-02-10 | — | — | EP | disclosed |