Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 1/20 | 0.70 |
| ▸ | S100A10 | P60903 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19289675 | 0.87 | ANXA2 (0.58) | ANXA2S100A10TSHRPOLBHTT | |
| SCHEMBL4208503 | 0.79 | TSHR (0.74) | TSHRPOLBHTTNPSR1ALDH1A1 | |
| SCHEMBL4206151 | 0.79 | TSHR (0.74) | TSHRPOLBHTTNPSR1ALDH1A1 | |
| SCHEMBL4208409 | 0.79 | HSD17B10 (0.65) | TSHRPOLBHTTNPSR1ALDH1A1 | |
| SCHEMBL4211130 | 0.74 | MEN1 (0.78) | TSHRHTTNPSR1ALDH1A1USP2 | |
| SCHEMBL4213359 | 0.72 | HCRTR2 (0.76) | TSHRPOLBHTTNPSR1ALDH1A1 | |
| SCHEMBL4211011 | 0.72 | LMNA (0.68) | TSHRHTTNPSR1ALDH1A1USP2 | |
| SCHEMBL6404093 | 0.72 | TSHR (0.74) | TSHRPOLBHTTNPSR1ALDH1A1 | |
| SCHEMBL4206962 | 0.72 | HCRTR2 (0.76) | ANXA2S100A10TSHRALDH1A1HPGD | |
| SCHEMBL18559232 | 0.71 | USP2 (0.79) | TSHRPOLBNPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210469-A1 | USE OF SUBSTITUTED THIO-1,2,4-TRIAZOLES FOR INCREASING STRESS TOLERANCE IN PLANTS | Bayer Cropscience AG (DE) | 2017-08-30 | — | — | EP | disclosed |