Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29818907 | 0.88 | AOC3 (0.46) | AOC3GALR3HSP90AA1NR1H4 | |
| SCHEMBL2207386 | 0.88 | AOC3 (0.46) | AOC3GALR3HSP90AA1NR1H4 | |
| SCHEMBL25818187 | 0.82 | AOC3 (0.50) | AOC3GALR3HSP90AA1NR1H4 | |
| SCHEMBL25818192 | 0.81 | KDM4E (0.46) | AOC3GALR3HSP90AA1NR1H4 | |
| SCHEMBL29818798 | 0.80 | AOC3 (0.46) | AOC3 | |
| SCHEMBL2207065 | 0.80 | AOC3 (0.46) | AOC3 | |
| SCHEMBL19291914 | 0.80 | AOC3 (0.46) | AOC3 | |
| SCHEMBL16084812 | 0.78 | LTB4R (0.52) | — | |
| SCHEMBL15150956 | 0.77 | AOC3 (0.43) | AOC3 | |
| SCHEMBL2207435 | 0.77 | CYSLTR2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210966-A1 | ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | Acucela, Inc. (US) | 2017-08-30 | — | — | EP | disclosed |