Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.42 |
| ▸ | TUBB | P07437 | 5/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254871 | 0.91 | SRC (0.54) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL11917498 | 0.91 | SRC (0.66) | SRCROCK1TUBB4ATUBBTUBA3C | |
| SCHEMBL19291990 | 0.89 | ROCK1 (0.43) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL19291578 | 0.89 | SRC (0.57) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL19292002 | 0.89 | SRC (0.52) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL19291803 | 0.87 | SRC (0.69) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL14047243 | 0.85 | ROCK1 (0.42) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL19291985 | 0.85 | ROCK1 (0.43) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL19291988 | 0.85 | ROCK1 (0.45) | SRCROCK1CYP3A4TUBB4ATUBB | |
| SCHEMBL12782494 | 0.84 | SRC (0.46) | SRCROCK1CYP3A4TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558085-B1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER | ATHENEX INC (US) | 2017-08-30 | — | — | EP | disclosed |