Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.41 |
| ▸ | TUBB | P07437 | 5/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254871 | 0.92 | SRC (0.54) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11917498 | 0.89 | SRC (0.66) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19291997 | 0.89 | SRC (0.54) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12782494 | 0.85 | SRC (0.46) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254287 | 0.85 | TUBB4A (0.48) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11917485 | 0.83 | SRC (0.58) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12782506 | 0.83 | SRC (0.56) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254138 | 0.81 | TUBB4A (0.60) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254932 | 0.81 | ROCK1 (0.43) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL253924 | 0.81 | SRC (0.57) | SRCTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558085-B1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER | ATHENEX INC (US) | 2017-08-30 | — | — | EP | disclosed |