Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132864 | 0.85 | SRC (0.62) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL254874 | 0.84 | SRC (0.75) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL3247613 | 0.79 | NPC1 (0.53) | SRCATMHTR2AHTR2CHTR2B | |
| SCHEMBL19291998 | 0.78 | CD274 (0.53) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL254875 | 0.76 | TUBB4A (0.73) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL12782501 | 0.75 | SRC (0.62) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL14143555 | 0.75 | SRC (0.48) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL255054 | 0.75 | SRC (0.66) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL254736 | 0.75 | SRC (0.73) | SRCABL1TUBB4ATUBBLYN | |
| SCHEMBL10297933 | 0.73 | SRC (0.64) | SRCABL1TUBB4ATUBBLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558085-B1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER | ATHENEX INC (US) | 2017-08-30 | — | — | EP | disclosed |