Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292474 | 0.89 | CYP19A1 (0.38) | CYP19A1KEAP1PDE10AKMT2ABRS3 | |
| SCHEMBL19292402 | 0.86 | CYP19A1 (0.52) | CYP19A1KEAP1PDE10AKMT2AMAPT | |
| SCHEMBL15707115 | 0.83 | PARP1 (0.40) | CYP19A1KEAP1PDE10AKMT2ABRS3 | |
| SCHEMBL19292316 | 0.82 | ACVR1 (0.37) | PDE10A | |
| SCHEMBL15707010 | 0.81 | HDAC1 (0.42) | CYP19A1BRS3 | |
| SCHEMBL19292264 | 0.80 | CYP1A2 (0.43) | CYP19A1PDE10ABRS3 | |
| SCHEMBL19292508 | 0.79 | PDE10A (0.55) | PDE10ABRS3 | |
| SCHEMBL19292260 | 0.79 | PDE10A (0.42) | PDE10AMAPT | |
| SCHEMBL19292016 | 0.79 | PDE10A (0.43) | CYP19A1PDE10ABRS3 | |
| SCHEMBL19291980 | 0.79 | PDE10A (0.37) | PDE10ABRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914589-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - SCIENCE PARK S P A (IT) | 2017-08-30 | — | — | EP | disclosed |