Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | BRS3 | P32247 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
| ▸ | GRPR | P30550 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292508 | 0.86 | PDE10A (0.55) | PDE10ABRS3HPGDS | |
| SCHEMBL19292150 | 0.83 | PDE10A (0.46) | PDE10ANPY5RBRS3HPGDS | |
| SCHEMBL19292513 | 0.82 | BRS3 (0.45) | PDE10ANPY5RBRS3NR1I2NMBR | |
| SCHEMBL19291980 | 0.81 | PDE10A (0.37) | PDE10ABRS3 | |
| SCHEMBL19292309 | 0.81 | HPGDS (0.45) | PDE10ANPY5RBRS3HPGDSCYP2D6 | |
| SCHEMBL19292010 | 0.80 | NLN (0.42) | PDE10A | |
| SCHEMBL19292018 | 0.79 | CYP19A1 (0.40) | PDE10ABRS3CYP19A1 | |
| SCHEMBL19292264 | 0.79 | CYP1A2 (0.43) | PDE10ABRS3CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL19291976 | 0.79 | PDE10A (0.43) | PDE10ABRS3 | |
| SCHEMBL19292035 | 0.78 | NPC1 (0.43) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914589-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - SCIENCE PARK S P A (IT) | 2017-08-30 | — | — | EP | disclosed |