Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21440853 | 1.00 | DPP7 (0.44) | DPP7CYP2C19CYP1A2GNAI3GNAO1 | |
| SCHEMBL12555652 | 0.86 | DPP7 (0.36) | DPP7CYP2C19CYP1A2GNAI3GNAO1 | |
| SCHEMBL13576256 | 0.86 | DPP7 (0.36) | DPP7CYP2C19CYP1A2GNAI3GNAO1 | |
| SCHEMBL28603573 | 0.85 | GSR (0.53) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL1456363 | 0.85 | GSR (0.53) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL24642321 | 0.85 | GSR (0.53) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| Water SCHEMBL28303757 | 0.83 | GSR (0.52) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL21089909 | 0.81 | DPP7 (0.42) | DPP7CYP2C19CYP1A2GNAI3GNAO1 | |
| SCHEMBL15959310 | 0.81 | DPP7 (0.50) | DPP7CYP2C19CYP1A2GNAI3GNAO1 | |
| SCHEMBL19726913 | 0.81 | ANPEP (0.41) | DPP7CYP1A2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392428-B2 | GLP-1 derivatives and uses thereof | NOVO NORDISK A/S (DK) | 2019-08-27 | — | — | US | disclosed |
| EP-3210998-A1 | METASTIN DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2017-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392428-B2 | GLP-1 derivatives and uses thereof | GLP1R, GIPR, VIP | DPP7 27/4885CYP2C19 882/4885CYP1A2 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.