Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882307 | 0.83 | DPP7 (0.50) | DPP7GNAI3GNAO1GNAI1SLC15A1 | |
| SCHEMBL21440853 | 0.81 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1SLC15A1 | |
| SCHEMBL19293334 | 0.81 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1SLC15A1 | |
| SCHEMBL24677673 | 0.81 | DPP7 (0.49) | DPP7GNAI3GNAO1GNAI1SLC15A1 | |
| SCHEMBL1456363 | 0.81 | GSR (0.53) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL24642321 | 0.81 | GSR (0.53) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL28603573 | 0.81 | GSR (0.53) | DPP7CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL13311872 | 0.81 | DPP7 (0.61) | DPP7GNAI3GNAO1GNAI1SLC15A1 | |
| SCHEMBL8231118 | 0.81 | DPP7 (0.61) | DPP7GNAI3GNAO1GNAI1SLC15A1 | |
| SCHEMBL8403553 | 0.80 | DPP7 (0.48) | DPP7GNAI3GNAO1GNAI1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448922-B1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC (CA) | 2014-08-20 | — | — | EP | disclosed |