Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19283992 | 0.99 | OGA (0.56) | OGAPLD1RETPANK3HTR3E | |
| SCHEMBL11914068 | 0.84 | PLD1 (0.49) | PLD1PANK3HTR3EHTR3BHTR3A | |
| SCHEMBL25900000 | 0.84 | OGA (0.62) | OGAPANK3HTR3EHTR3BHTR3A | |
| SCHEMBL19296128 | 0.80 | OGA (0.51) | OGAKDM4EUSP2ALDH1A1CYP1A2 | |
| SCHEMBL14375620 | 0.79 | MEN1 (0.45) | OGAPLD1RETPANK3KDM4E | |
| Hydrochloric Acid SCHEMBL19283935 | 0.79 | OGA (0.50) | OGAKDM4EUSP2ALDH1A1CYP1A2 | |
| SCHEMBL2617748 | 0.78 | PLD1 (0.49) | PLD1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27772209 | 0.78 | PLD1 (0.43) | OGAPLD1PANK3HTR3EHTR3B | |
| SCHEMBL3605635 | 0.78 | OGA (0.55) | OGAPLD1PANK3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL2119097 | 0.77 | PLD1 (0.47) | PLD1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419971-B1 | GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2022-04-20 | — | — | EP | disclosed |
| US-20210186958-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2021-06-24 | — | — | US | disclosed |
| US-10556902-B2 | Glycosidase inhibitors | ASCENEURON SA (CH) | 2020-02-11 | — | — | US | disclosed |
| US-20190055239-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2019-02-21 | — | — | US | disclosed |
| WO-2017144633-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017144639-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556902-B2 | Glycosidase inhibitors | ENGASE, GAA, GLA | OGA 69/4885PLD1 4705/4885RET 2662/4885 |
| US-20210186958-A1 | GLYCOSIDASE INHIBITORS | ENGASE, GAA, GLA | OGA 73/4885PLD1 4683/4885RET 2945/4885 |
| US-20190055239-A1 | GLYCOSIDASE INHIBITORS | ENGASE, GAA, GLA | OGA 69/4885PLD1 4705/4885RET 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.