SCHEMBL19296128

SCHEMBL19296128

CC(C)C(O)c1cnc(N2CCNCC2)nc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGA O60502 3/20 0.51
ALDH1A1 P00352 5/20 0.47
KDM4E B2RXH2 2/20 0.47
TAAR1 Q96RJ0 1/20 0.44
CASP1 P29466 4/20 0.38
TSHR P16473 3/20 0.38
CYP1A2 P05177 3/20 0.38
CASP7 P55210 3/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 1/20 0.38
HRH1 P35367 1/20 0.38
USP2 O75604 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CASP4 P49662 1/20 0.37
CASP5 P51878 1/20 0.37
MAPT P10636 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19283935 0.98 OGA (0.50) OGAALDH1A1KDM4ETAAR1CASP1
SCHEMBL18948987 0.83 ALDH1A1 (0.53) ALDH1A1KDM4ETAAR1CASP1TSHR
Hydrochloric Acid SCHEMBL25309902 0.81 ALDH1A1 (0.56) ALDH1A1KDM4ETAAR1CASP1TSHR
SCHEMBL19296234 0.80 OGA (0.57) OGAALDH1A1KDM4ECYP1A2HSD17B10
Hydrochloric Acid SCHEMBL19283992 0.79 OGA (0.56) OGAALDH1A1KDM4ECYP1A2HSD17B10
SCHEMBL23304816 0.76 ALDH1A1 (0.53) ALDH1A1KDM4ETAAR1CASP1TSHR
SCHEMBL16651942 0.75 TSHR (0.58) ALDH1A1KDM4ETAAR1CASP1TSHR
SCHEMBL16651829 0.75 TSHR (0.58) ALDH1A1KDM4ETAAR1CASP1TSHR
SCHEMBL16651828 0.75 TSHR (0.58) ALDH1A1KDM4ETAAR1CASP1TSHR
SCHEMBL7991455 0.73 ALDH1A1 (0.59) ALDH1A1KDM4ETAAR1CASP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3419972-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2023-07-26 EP disclosed
EP-3419971-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-04-20 EP disclosed
US-20210186958-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-06-24 US disclosed
US-10556902-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2020-02-11 US disclosed
US-20190055239-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2019-02-21 US disclosed
WO-2017144639-A1 GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2017-08-31 WO disclosed
WO-2017144633-A1 GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2017-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10556902-B2 Glycosidase inhibitors ENGASE, GAA, GLA OGA 69/4885ALDH1A1 716/4885KDM4E 1636/4885
US-20210186958-A1 GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA OGA 73/4885ALDH1A1 635/4885KDM4E 1588/4885
US-20190055239-A1 GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA OGA 69/4885ALDH1A1 716/4885KDM4E 1636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.