Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989133 | 0.92 | PDK2 (0.54) | PDK2MAOBTDP2PGRALOX5 | |
| SCHEMBL21666300 | 0.89 | PDK2 (0.43) | PDK2TDO2ADORA2AADORA1MEN1 | |
| SCHEMBL21925960 | 0.88 | PDK2 (0.45) | PDK2AKR1A1AKR1B1TDP2PGR | |
| SCHEMBL25124911 | 0.88 | PDK2 (0.47) | PDK2ADORA2AADORA1MEN1GAA | |
| SCHEMBL23989203 | 0.87 | PDK2 (0.45) | PDK2MEN1KMT2AAKR1A1AKR1B1 | |
| SCHEMBL19299404 | 0.87 | PDK2 (0.41) | PDK2TDO2ADORA2AADORA1MEN1 | |
| SCHEMBL23989130 | 0.85 | PDK2 (0.49) | PDK2TDP2PGR | |
| SCHEMBL20687381 | 0.85 | PDK2 (0.46) | PDK2MEN1KMT2AAKR1A1AKR1B1 | |
| SCHEMBL19299490 | 0.85 | PDK2 (0.41) | PDK2AKR1A1AKR1B1TDP2PGR | |
| SCHEMBL20618858 | 0.85 | PDK2 (0.45) | PDK2AKR1A1AKR1B1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-11538996-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| WO-2021214348-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-10-28 | — | — | WO | disclosed |
| EP-3419960-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-10454041-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| WO-2017144150-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10454041-B2 | Materials for organic electroluminescent devices | RIF1, INTS9, LEF1 | PDK2 1325/4885TDO2 1201/4885ADORA2A 4472/4885 |
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2E1, GPX1, ERCC1 | PDK2 461/4885TDO2 1244/4885ADORA2A 3318/4885 |
| US-11538996-B2 | Materials for organic electroluminescent devices | RIF1, INTS9, LEF1 | PDK2 1325/4885TDO2 1201/4885ADORA2A 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.