Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300113 | 0.86 | LMNA (0.71) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL19300268 | 0.83 | LMNA (0.77) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL19300080 | 0.83 | LMNA (1.00) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL19300001 | 0.83 | LMNA (0.67) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL19300217 | 0.81 | LMNA (0.61) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL19300000 | 0.81 | LMNA (0.61) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL8879725 | 0.81 | MEN1 (0.75) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL10833328 | 0.80 | KDM4E (0.71) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL19300084 | 0.80 | OGA (0.68) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL17551318 | 0.79 | OGA (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186243-B1 | GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2021-07-21 | — | — | EP | disclosed |
| EP-3419976-B1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON SA (CH) | 2021-04-07 | — | — | EP | disclosed |
| WO-2017144637-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |