Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301735 | 0.82 | PDE6D (0.41) | ABCC1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL19284370 | 0.81 | CYP1A2 (0.48) | ABCC1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL19301744 | 0.76 | MAPK1 (0.47) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL18152765 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL19301627 | 0.74 | KDM4E (0.43) | ABCC1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL18152809 | 0.72 | TSHR (0.65) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL19301724 | 0.71 | PDE10A (0.43) | ABCC1KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL19301734 | 0.71 | KDM4E (0.40) | ABCC1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL19301779 | 0.70 | NOTUM (0.41) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL19301633 | 0.70 | TDP1 (0.46) | KDM4EHSD17B10ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147102-A1 | HETEROARYL INHIBITORS OF PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2017-08-31 | — | — | WO | disclosed |