Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213223 | 0.94 | TSHR (0.57) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL5071460 | 0.85 | TSHR (0.63) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL27576611 | 0.84 | TSHR (0.61) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL6619406 | 0.81 | TSHR (0.58) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL652738 | 0.81 | TSHR (0.58) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL18152746 | 0.79 | TLR8 (0.48) | TSHRHPGDTLR8 | |
| SCHEMBL11875015 | 0.78 | TSHR (0.54) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL9321137 | 0.78 | TP53 (0.72) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18152846 | 0.78 | TSHR (0.61) | TSHRNR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL18152765 | 0.76 | KDM4E (0.59) | TSHRNR1H3KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606666-B2 | Imidazoles and imidazolium cations with exceptional alkaline stability | CORNELL UNIVERSITY (US) | 2026-04-21 | — | — | US | disclosed |
| EP-4108691-A1 | IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | Cornell University (US) | 2022-12-28 | — | — | EP | disclosed |
| EP-4108691-A1 | IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | Cornell University (US) | 2022-12-28 | — | — | EP | disclosed |
| EP-3283535-B1 | POLYMERS COMPRISING IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | UNIV CORNELL (US) | 2022-08-10 | — | — | EP | disclosed |
| US-20220127413-A1 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | CORNELL UNIVERSITY (US) | 2022-04-28 | — | — | US | disclosed |
| US-20220127413-A1 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | CORNELL UNIVERSITY (US) | 2022-04-28 | — | — | US | disclosed |
| US-11242432-B2 | Imidazoles and imidazolium cations with exceptional alkaline stability | CORNELL UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| US-11242432-B2 | Imidazoles and imidazolium cations with exceptional alkaline stability | CORNELL UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| CN-108026213-B | Imidazole and imidazolium cations with special base stability | 康奈尔大学 | 2021-11-02 | — | — | CN | disclosed |
| US-20190047963-A1 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | CORNELL UNIVERSITY (US) | 2019-02-14 | — | — | US | disclosed |
| US-20190047963-A1 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | CORNELL UNIVERSITY (US) | 2019-02-14 | — | — | US | disclosed |
| CN-108026213-A | Imidazoles and glyoxaline cation with special alkaline stability | 康奈尔大学 | 2018-05-11 | — | — | CN | disclosed |
| EP-3283535-A2 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | Cornell University (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168468-A2 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | CORNELL UNIVERSITY (US) | 2016-10-20 | — | — | WO | disclosed |
| WO-2016168468-A2 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | CORNELL UNIVERSITY (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127413-A1 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | ALPI, ITPA, ITPR2 | TSHR 4548/4885NR1H3 4813/4885KDM4E 1492/4885 |
| US-20190047963-A1 | IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY | ALPI, ITPA, ITPR2 | TSHR 4548/4885NR1H3 4813/4885KDM4E 1492/4885 |
| US-11242432-B2 | Imidazoles and imidazolium cations with exceptional alkaline stability | ALPI, ITPA, ITPR2 | TSHR 4548/4885NR1H3 4813/4885KDM4E 1492/4885 |
| US-12606666-B2 | Imidazoles and imidazolium cations with exceptional alkaline stability | SCO2, RCC1, SMC2 | TSHR 1886/4885NR1H3 2394/4885KDM4E 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.