Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30045024 | 0.83 | METAP1 (0.31) | — | |
| SCHEMBL19939298 | 0.77 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL105008 | 0.74 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL2201094 | 0.71 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL22458613 | 0.71 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL30837730 | 0.71 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL23669706 | 0.67 | REN (0.30) | — | |
| SCHEMBL23688110 | 0.67 | REN (0.30) | — | |
| SCHEMBL23688109 | 0.67 | REN (0.30) | — | |
| SCHEMBL19285730 | 0.67 | REN (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147410-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2017-08-31 | — | — | WO | disclosed |