Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084876 | 0.76 | KIF11 (0.32) | CA1CA2 | |
| SCHEMBL15177636 | 0.75 | CA1 (0.36) | CA12CA7CA9CA14CA1 | |
| SCHEMBL19302717 | 0.71 | CES1 (0.34) | — | |
| SCHEMBL19302728 | 0.69 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL9630685 | 0.69 | ALOX5AP (0.32) | CA1CA2 | |
| SCHEMBL24450920 | 0.68 | CA12 (0.49) | CA12CA7CA9CA14CA2 | |
| SCHEMBL3871336 | 0.68 | — | — | |
| Potassium Ion SCHEMBL9632475 | 0.67 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL9630739 | 0.67 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL10480499 | 0.67 | ALOX5AP (0.31) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |