SCHEMBL19302765

CC(C)(C)OC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)CCC(=O)c2ccccc2B2OC(C)(C)C(C)(C)O2)[C@H]2OC(C)(C)O[C@H]21

nearest known ligand 0.58

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	1/20	0.43

▸	TRPM2	O94759	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19302919	0.85	RXFP1 (0.41)	RXFP1TRPM2
SCHEMBL19302748	0.85	RXFP1 (0.41)	RXFP1TRPM2
SCHEMBL19302916	0.85	RXFP1 (0.41)	RXFP1TRPM2
SCHEMBL22837891	0.83	RXFP1 (0.51)	RXFP1TRPM2
SCHEMBL20508960	0.80	RXFP1 (0.42)	RXFP1
SCHEMBL19302870	0.80	RXFP1 (0.42)	RXFP1
SCHEMBL19302804	0.80	RXFP1 (0.59)	RXFP1
SCHEMBL20699831	0.76	RXFP1 (0.52)	RXFP1
SCHEMBL19302872	0.76	RXFP1 (0.42)	RXFP1
SCHEMBL20699834	0.75	PI4KA (0.62)	RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017059411-A9	INHIBITORS OF MENAQUINONE BIOSYNTHESIS	MEMORIAL SLOAN-KETTERING CANCER CENTER (US)	2017-08-31	—	—	WO	disclosed