⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16116343 | 0.75 | — | — | |
| SCHEMBL2848719 | 0.74 | — | — | |
| SCHEMBL201781 | 0.74 | — | — | |
| SCHEMBL1007610 | 0.74 | — | — | |
| SCHEMBL577167 | 0.74 | — | — | |
| Methane SCHEMBL27549579 | 0.72 | — | — | |
| SCHEMBL28748970 | 0.70 | — | — | |
| SCHEMBL19778794 | 0.70 | — | — | |
| SCHEMBL4860801 | 0.68 | GRM5 (0.46) | — | |
| SCHEMBL15870897 | 0.67 | GRM5 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410305-B2 | Intermediates and methods for the preparation of epothilones | KOSAN BIOSCIENCES INCORPORATED (US) | 2013-04-02 | — | — | US | disclosed |
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |
| US-8030503-B2 | Process for the preparation of epothilones | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-10-04 | — | — | US | disclosed |
| US-7955824-B2 | Methods of making epothilones | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100267943-A1 | INTERMEDIATES AND METHODS FOR THE PREPARATION OF EPOTHILONES | KOSAN BIOSCIENCES INCORPORATED | 2010-10-21 | — | — | US | disclosed |
| WO-2009064800-A1 | INTERMEDIATES AND METHODS FOR THE PREPARATION OF EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20080319211-A1 | PROCESS FOR THE PREPARATION OF EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2008-12-25 | — | — | US | disclosed |
| WO-2008141234-A2 | METHODS OF MAKING EPOTHILONES | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008141130-A1 | PROCESS FOR THE PREPARATION OF EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-7125442-B2 | Lightfast additive having UV-absorbing moiety and ink composition including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-10-24 | — | — | US | disclosed |
| US-20040237837-A1 | Lightfast additive having UV-absorbing moiety and ink composition including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-12-02 | — | — | US | disclosed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4472309-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4264498-A | REACTED WITH AN ACID, ITS ACID HALIDE, OR ANHYDRIDE IN THE PRESENCE OF BORON TRIHALIDE AND AN ORGANIC BASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |