SCHEMBL1007610

SCHEMBL1007610

[C]#Cc1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15870993 0.78 GRM5 (0.68)
SCHEMBL577167 0.74
SCHEMBL2848719 0.74
SCHEMBL1930368 0.74
SCHEMBL201781 0.74
SCHEMBL193706 0.74
Methane SCHEMBL27549579 0.72
SCHEMBL5805253 0.70
SCHEMBL19778794 0.70
SCHEMBL16116343 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9803240-B2 Stabilized nucleic acid dark quencher-fluorophore probes BIOSEARCH TECHNOLOGIES, INC. (US) 2017-10-31 US claimed
EP-2757091-B1 Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes BIOSEARCH TECH INC (US) 2017-06-28 EP claimed
EP-2757091-A1 Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes Biosearch Technologies, Inc. (US) 2014-07-23 EP claimed
US-20140194611-A1 STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES BIOSEARCH TECHNOLOGIES, INC. (US) 2014-07-10 US claimed
CN-114401966-A Method for producing cyclic imide compound, composition, compound 富士胶片株式会社 2022-04-26 CN disclosed
US-9803240-B2 Stabilized nucleic acid dark quencher-fluorophore probes BIOSEARCH TECHNOLOGIES, INC. (US) 2017-10-31 US disclosed
EP-2757091-B1 Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes BIOSEARCH TECH INC (US) 2017-06-28 EP disclosed
EP-2757091-A1 Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes Biosearch Technologies, Inc. (US) 2014-07-23 EP disclosed
US-20140194611-A1 STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES BIOSEARCH TECHNOLOGIES, INC. (US) 2014-07-10 US disclosed
US-8674094-B2 Stabilized nucleic acid dark quencher-fluorophore probes BIOSEARCH TECHNOLOGIES, INC. (US) 2014-03-18 US disclosed
CN-102037144-B Stabilized nucleic acid dark quencher-fluorophore probes BIOSEARCH TECHNOLOGIES INC 2013-09-25 CN disclosed
US-8466266-B2 Stabilized nucleic acid dark quencher-fluorophore probes BIOSEARCH TECHNOLOGIES, INC. (US) 2013-06-18 US disclosed
US-20030170680-A1 Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines FROEHLER BRIAN (US) 2003-09-11 US disclosed
US-20030096980-A1 Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines ISIS PHARMACEUTICALS, INC. 2003-05-22 US disclosed
EP-1256589-A2 Oligomers containing modified pyrimidines ISIS PHARMACEUTICALS, INC. (US) 2002-11-13 EP disclosed
EP-0637965-B1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES ISIS PHARMACEUTICALS INC (US) 2002-10-16 EP disclosed
WO-2002036548-A2 METHOD FOR STEREOSELECTIVELY PRODUCING HYDRAZINO CYCLOALKENES AND DIAMINO CYCLOALKANES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-10 WO disclosed
US-6380368-B1 GENETIC ENGINEERING ISIS PHARMACEUTICALS, INC. 2002-04-30 US disclosed
US-5830653-A ABILITY TO INHIBIT GENE EXPRESSION GILEAD SCIENCES, INC. (US) 1998-11-03 US disclosed
US-5645985-A USED FOR DIAGNOSIS TO DETECT VIRUSES OR DISEASED CONDITIONS GILEAD SCIENCES, INC. (US) 1997-07-08 US disclosed