Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.39 |
| ▸ | PPARG | P37231 | 13/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930445 | 1.00 | PPARA (0.39) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL13843997 | 1.00 | PPARA (0.39) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL3980959 | 0.96 | PPARA (0.37) | PPARAPPARGPPARD | |
| SCHEMBL1928816 | 0.92 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL1929321 | 0.92 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL13843953 | 0.92 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL1930111 | 0.92 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL1930106 | 0.92 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL1929322 | 0.92 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL1929971 | 0.92 | PPARA (0.46) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956077-B2 | 2-{-3,′2-(phenyl)-oxazol-4-ylmethoxyl-cyclohexyl methoxy}-propionic acid derivatives used as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-06-07 | — | — | US | disclosed |