Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.37 |
| ▸ | PPARG | P37231 | 14/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13843997 | 0.96 | PPARA (0.39) | PPARAPPARGPPARD | |
| SCHEMBL1930447 | 0.96 | PPARA (0.39) | PPARAPPARGPPARD | |
| SCHEMBL1930445 | 0.96 | PPARA (0.39) | PPARAPPARGPPARD | |
| SCHEMBL3974209 | 0.92 | PPARA (0.37) | PPARAPPARGPPARD | |
| SCHEMBL3975429 | 0.91 | PPARA (0.36) | PPARAPPARGPPARD | |
| SCHEMBL3972003 | 0.91 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL13843953 | 0.88 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL1930106 | 0.88 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL1928816 | 0.88 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL1930111 | 0.88 | PPARA (0.40) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778655-B1 | 2 - { - 3 2 - (PHENYL)-OXAZOL-4-YLMETHOXYL-CYCLOHEXYLMETHOXY}-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDS (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | EP | disclosed |