2-Phenylquinoline

2-Phenylquinoline

SCHEMBL19304552

Cc1cccc(-c2ccccn2)c1.[Ir].c1ccc(-c2ccc3ccccc3n2)cc1.c1ccc(-c2ccc3ccccc3n2)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.49
BCHE P06276 1/20 0.48
ACHE P22303 1/20 0.48
NPC1 O15118 5/20 0.48
RAB9A P51151 5/20 0.48
AR P10275 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
LMNA P02545 2/20 0.45
KMO O15229 1/20 0.45
PDE10A Q9Y233 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TGFBR1 P36897 1/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL500925 0.87 NPC1 (0.54) BCHEACHENPC1RAB9AAR
SCHEMBL31038141 0.86 NPC1 (0.55) BCHEACHENPC1RAB9AAR
SCHEMBL3405046 0.86 NPC1 (0.55) BCHEACHENPC1RAB9AAR
SCHEMBL31492170 0.83 GRM5 (0.60) GRM5BCHEACHENPC1RAB9A
SCHEMBL16783703 0.83 GRM5 (0.60) GRM5BCHEACHENPC1RAB9A
SCHEMBL20080983 0.82 NPC1 (0.56) NPC1RAB9AARCYP1A2CYP3A4
SCHEMBL29638128 0.81 GRM5 (0.62) GRM5BCHEACHENPC1RAB9A
SCHEMBL215712 0.81 GRM5 (0.62) GRM5BCHEACHENPC1RAB9A
SCHEMBL29427960 0.80 GRM5 (0.60) GRM5BCHEACHENPC1RAB9A
SCHEMBL14979453 0.78 GRM5 (0.59) GRM5BCHEACHENPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3214668-B1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INST APPLIED CHEMISTRY CAS (CN) 2019-08-21 EP claimed
US-10355230-B2 Red organic electroluminescent device and preparation method thereof Changchung Institute of Applied Chemistry, Chinese Academy of Sciences (CN) 2019-07-16 US claimed
US-10177324-B2 White organic electroluminescent device and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-08 US claimed
US-20180248138-A1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-08-30 US claimed
US-20170317307-A1 RED ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2017-11-02 US claimed
EP-3214668-A1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) 2017-09-06 EP claimed
EP-3214665-A1 RED ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) 2017-09-06 EP claimed
EP-3214668-B1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INST APPLIED CHEMISTRY CAS (CN) 2019-08-21 EP disclosed
US-10355230-B2 Red organic electroluminescent device and preparation method thereof Changchung Institute of Applied Chemistry, Chinese Academy of Sciences (CN) 2019-07-16 US disclosed
US-10177324-B2 White organic electroluminescent device and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-08 US disclosed
US-20180248138-A1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-08-30 US disclosed
US-20170317307-A1 RED ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2017-11-02 US disclosed
EP-3214668-A1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) 2017-09-06 EP disclosed
EP-3214665-A1 RED ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) 2017-09-06 EP disclosed