SCHEMBL215712

SCHEMBL215712

Cc1cccc(-c2ccccn2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 4/20 0.62
TGFBR1 P36897 1/20 0.57
DCTPP1 Q9H773 1/20 0.54
BCHE P06276 1/20 0.53
ACHE P22303 1/20 0.53
KDM4E B2RXH2 4/20 0.50
LMNA P02545 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CYP2A6 P11509 1/20 0.50
KMO O15229 1/20 0.49
IDO1 P14902 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29638128 1.00 GRM5 (0.62) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL29427960 0.98 GRM5 (0.60) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL31492170 0.98 GRM5 (0.60) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL16783703 0.98 GRM5 (0.60) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL14979453 0.96 GRM5 (0.59) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL19009231 0.91 GRM5 (0.57) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL13483217 0.90 GRM5 (0.61) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL13799169 0.87 GRM5 (0.50) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL30574663 0.87 GRM5 (0.50) GRM5TGFBR1DCTPP1BCHEACHE
SCHEMBL31039977 0.85 GRM5 (0.56) GRM5TGFBR1DCTPP1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160354-A Method for efficiently synthesizing aryl silicon compound 南阳师范学院 2022-10-11 CN claimed
US-20200384451-A1 PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-12-10 US claimed
US-20070099958-A1 Protease inhibitors PROZYMEX A/S (DK) 2007-05-03 US claimed
EP-1638925-A1 PROTEASE INHIBITORS Prozymex A/S (DK) 2006-03-29 EP claimed
WO-2004110988-A1 PROTEASE INHIBITORS PROZYMEX A/S (DK) 2004-12-23 WO claimed
CN-119439625-A Negative photosensitive resin composition, pattern forming method, cured coating film forming method, interlayer insulating film, surface protective film, and electronic component 信越化学工业株式会社 2025-02-14 CN disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-27 US disclosed
CN-113527101-B Novel compound, polymer, process for producing the same, photosensitive resin composition, pattern forming process, cured film, and electronic component 信越化学工业株式会社 2024-04-23 CN disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
CN-117501180-A Laminate, method for producing laminate, and method for forming pattern 信越化学工业株式会社 2024-02-02 CN disclosed
US-6613747-B2 Erythromycins to treat community-acquired pneumonia and upper and lower respiratory tract, skin and soft tissue, hospital-acquired lung, bone and joint infections; Staphyloccus; Enterococcus; Moraxella; Hemophilus; antibiotic resistance ORTHO-MCNEIL PHARMACEUTICAL, INC. 2003-09-02 US disclosed
US-20030013663-A1 6-O-CARBAMOYL KETOLIDE ANTIBACTERIALS ORTHO-MCNEIL PHARMACEUTICAL, INC. 2003-01-16 US disclosed
US-6472372-B1 6-O-Carbamoyl ketolide antibacterials ORTHO-MCNEIL PHARMACEUTICALS, INC. 2002-10-29 US disclosed
US-20020115620-A1 6-0-carbamoyl ketolide antibacterials ORTHO-MCNEIL PHARMACEUTICAL, INC. 2002-08-22 US disclosed
US-6071670-A PHOTORESIST RESIN COMPRISING PHOTOACID GENERATING COMPOUND AND AN ACID HYDROLYZABLE OLIGOMER HAVING ALICYCLIC OR POLYCONDENSED AROMATIC BACKBONE; ALKALI DEVELOPMENT WITH HIGH RESOLUTION, DRY ETCH RESISTANCE KABUSHIKI KAISHA TOSHIBA (JP) 2000-06-06 US disclosed
EP-0594179-B1 N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivate YASHIMA KAGAKU KOGYO KK (JP) 1996-09-25 EP disclosed
US-5354905-A N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivative YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) 1994-10-11 US disclosed
EP-0594179-A1 N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivate YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) 1994-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099958-A1 Protease inhibitors CTSC, DPP7, BACE1 GRM5 2091/4885TGFBR1 2671/4885DCTPP1 1813/4885
US-20030013663-A1 6-O-CARBAMOYL KETOLIDE ANTIBACTERIALS Q6ZSR9, KDM4E, HK1 GRM5 3350/4885TGFBR1 4583/4885DCTPP1 2950/4885
US-20200384451-A1 PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF CPNE4, PPOX, PDCD5 GRM5 836/4885TGFBR1 4308/4885DCTPP1 1556/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP GRM5 1993/4885TGFBR1 4267/4885DCTPP1 4299/4885
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM GRM5 2302/4885TGFBR1 2554/4885DCTPP1 4873/4885
US-20020115620-A1 6-0-carbamoyl ketolide antibacterials Q6ZSR9, HK1, KDM4E GRM5 3271/4885TGFBR1 4475/4885DCTPP1 2926/4885
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OCIAD1 GRM5 2908/4885TGFBR1 1187/4885DCTPP1 4863/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 GRM5 3656/4885TGFBR1 3010/4885DCTPP1 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.