Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17838126 | 0.98 | PREP (0.38) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL16468141 | 0.88 | GAA (0.46) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL17838127 | 0.86 | PREP (0.38) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL6155918 | 0.81 | PREP (0.44) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL9479693 | 0.81 | ALDH1A1 (0.46) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL16411847 | 0.81 | ALDH1A1 (0.46) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL17782436 | 0.81 | MAPT (0.61) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL16467970 | 0.80 | SCN9A (0.44) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL16411531 | 0.80 | RAD52 (0.44) | PREPGAAMAPTRAB9AKDM4E | |
| SCHEMBL16411425 | 0.80 | PREP (0.40) | PREPGAAMAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3024833-B1 | NOVEL INDOLIZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2017-09-06 | — | — | EP | disclosed |