SCHEMBL19304801

SCHEMBL19304801

O=C(Cn1nc(C(F)F)cc1C(F)F)N1CCC(c2nc(C3=NOC(c4[c]c(Cl)ccc4)C3)cs2)CC1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19304806 0.92 FAAH (0.48) FAAH
SCHEMBL18702984 0.89 FAAH (0.51) FAAH
SCHEMBL18036483 0.89 FAAH (0.51) FAAH
SCHEMBL1998670 0.88 FAAH (0.51) FAAH
SCHEMBL19304805 0.87 FAAH (0.50) FAAH
SCHEMBL19304799 0.87 FAAH (0.50) FAAH
SCHEMBL29263762 0.87 FAAH (0.50) FAAH
SCHEMBL28860651 0.87 FAAH (0.48) FAAH
SCHEMBL15808707 0.86 FAAH (0.51) FAAH
SCHEMBL20301469 0.86 FAAH (0.51) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2819518-B1 ACTIVE COMPOUND COMBINATIONS CONTAINING A THIAZOYLISOXAZOLINE AND A FUNGICIDE BAYER IP GMBH (DE) 2017-09-06 EP claimed