Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 4/20 | 0.53 |
| ▸ | PRKCA | P17252 | 6/20 | 0.50 |
| ▸ | TLR4 | O00206 | 6/20 | 0.48 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325678 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL2201385 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL10325677 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL2201391 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL2199693 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL2199694 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL10325676 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL10325165 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL10325164 | 0.93 | TK2 (0.54) | TK2PRKCATLR4LY96 | |
| SCHEMBL2200260 | 0.92 | TK2 (0.51) | TK2PRKCATLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2716293-B1 | ANTI-TUMOR AGENT | UNIV KINKI (JP) | 2017-09-06 | — | — | EP | disclosed |