SCHEMBL10325677

SCHEMBL10325677

CCCCCCCCCCCCCC(=O)O[C@H]1[C@@H](O)[C@@H](CO)OC(O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TK2 O00142 4/20 0.54
▸ PRKCA P17252 6/20 0.51
▸ TLR4 O00206 4/20 0.49
▸ LY96 Q9Y6Y9 4/20 0.47
▸ LGALS8 O00214 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10325676 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL10325164 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL2201385 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL2199694 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL2201391 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL2199693 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL10325678 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL10325165 1.00 TK2 (0.54) TK2PRKCATLR4LY96LGALS8
SCHEMBL10326198 0.94 LGALS8 (0.49) TK2PRKCATLR4LY96LGALS8
SCHEMBL10326200 0.94 LGALS8 (0.49) TK2PRKCATLR4LY96LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130134-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-04-27 — — US disclosed
EP-4121060-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF Board of Regents, The University of Texas System (US) 2023-01-25 — — EP disclosed
WO-2021188586-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-09-23 — — WO disclosed
EP-2663314-A2 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES The University of Texas M.D. Anderson Cancer (US) 2013-11-20 — — EP disclosed
US-20120276108-A1 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES INTERTECH BIO (US) 2012-11-01 — — US disclosed
WO-2012097052-A2 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES INTERTECH BIO, LLC (US) 2012-07-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130134-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF G6PD, FBP1, ALDOA TK2 237/4885PRKCA 3265/4885TLR4 658/4885
US-20120276108-A1 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES IGF1R, IRS1, IGFBP1 TK2 238/4885PRKCA 1662/4885TLR4 454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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