Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD1 | P21728 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | DRD5 | P21918 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466993 | 0.90 | FPR2 (0.63) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL1068103 | 0.79 | FPR2 (0.74) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL1067508 | 0.77 | FPR2 (0.72) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL21445275 | 0.77 | FPR2 (1.00) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL3025305 | 0.76 | FPR2 (0.71) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL1070185 | 0.76 | FPR2 (0.71) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL31322328 | 0.76 | RAD52 (0.72) | FPR2DRD2DRD1HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL23039348 | 0.76 | FPR2 (0.98) | FPR2DRD2DRD1HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL1070453 | 0.76 | FPR2 (0.70) | FPR2DRD2DRD1HRH1DRD3 | |
| SCHEMBL5801554 | 0.76 | FPR2 (0.70) | FPR2DRD2DRD1HRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781272-B1 | USE OF COMPOUNDS ACTIVE ON THE SIGMA RECEPTOR FOR THE TREATMENT OF MECHANICAL ALLODYNIA | ESTEVE LABOR DR (ES) | 2017-09-06 | — | — | EP | claimed |