SCHEMBL1930697

SCHEMBL1930697

OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62076 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL123489 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL8617343 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL959164 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL1686885 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL8619106 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL926705 0.97 TSHR (0.37) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL21906296 0.93 TSHR (0.36) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL21426 0.90 TSHR (0.38) TSHRUSP2MAPTKDM4ETDP1
Fluoride SCHEMBL28773810 0.87 TSHR (0.37) TSHRUSP2MAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073288-A Preparation method of fluorine-containing acrylate 深圳华益兄弟科技有限公司 2022-09-20 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-0367583-B1 FLUORINATED, ACRYLAMIDE-FUNCTIONAL MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-04 EP claimed
EP-0367582-B1 O-HYDROXYALKYLATION OF 1,1-DIHYDROPERFLUORINATED ALCOHOLS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-02-03 EP claimed
EP-0518534-A1 O-Hydroxyalkylation of 1,1,-dihydro fluorinated alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-12-16 EP claimed
EP-0367583-A2 Fluorinated, acrylamide-functional monomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-09 EP claimed
EP-0367582-A1 O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-09 EP claimed
US-4906792-A O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US claimed
WO-2025094091-A1 MATERIAL FOR FORMING A PATTERNING COATING COMPRISING A PHASE-CHANGE MATERIAL AND DEVICES INCORPORATING THE SAME OTI LUMIONICS INC. (CA) 2025-05-08 WO disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-11993710-B2 Composite solid state electrolyte and lithium ion battery containing the same WILDCAT DISCOVERY TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
WO-2022240599-A2 COMPOSITE SOLID STATE ELECTROLYTE AND LITHIUM ION BATTERY CONTAINING THE SAME WILDCAT DISCOVERY TECHNOLOGIES, INC. (US) 2022-11-17 WO disclosed
CN-115073288-A Preparation method of fluorine-containing acrylate 深圳华益兄弟科技有限公司 2022-09-20 CN disclosed
EP-0375610-A2 Perfluoroalkylthioglycosides CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
EP-0367582-A1 O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-09 EP disclosed
US-4906792-A O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US disclosed
US-4778862-A Fluorine and acrylic modified silicone resins THE GLIDDEN COMPANY (US) 1988-10-18 US disclosed
US-4167546-A Adhesive composition KORSHAK VASILY V 1979-09-11 US disclosed
US-4022609-A MITICIDES PPG INDUSTRIES, INC. (US) 1977-05-10 US disclosed